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Adjunct therapy for the dispersal [by dissolution and/or expulsion] of stones in the common bile duct. To be used in combination with chenodeoxycholic acid. It has been demonstrated that if ROWACHOL® is combined with either low or medium dose chenodeoxycholic acid, the gallstone dissolution rate is greater than if the same dose of chenodeoxycholic acid is used alone. Combined therapy enables a reduced dose of chenodeoxycholic acid to be used and there is therefore a lower incidence of side effects. ROWACHOL® increases biliary secretion, relieves spasm of the bile ducts, enhances metabolic liver function, reducing biliary stasis. By inhibiting HMGCoA reductase endogenous cholesterol production is reduced, maintaining the bile above saturation level, assisting dissolution of gallstones and preventing precipitation of further stones.
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